Analysis of the docking interaction between Sld2 and Clb5 in budding yeast
| dc.contributor.author | Mikhailova, Valentina | |
| dc.contributor.other | Tartu Ülikool. Loodus- ja täppisteaduste valdkond | et |
| dc.contributor.other | Tartu Ülikool. Tehnoloogiainstituut | et |
| dc.date.accessioned | 2021-07-01T11:27:13Z | |
| dc.date.available | 2021-07-01T11:27:13Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | The cell cycle of Saccharomyces cerevisiae is governed by cyclin dependent kinases (Cdks), which are activated by periodically synthesized and degraded cyclins. The substrate target-ing by a cyclin-Cdk complex is mediated by the active site on the Cdk and the cyclin docking pocket. Docking interactions between short linear motifs (SLiMs) in target proteins and cy-clin-dependent kinases are shown to be critical regulators of different cell cycle events. SLiMs function in almost every pathway due to their role in regulatory function and signal transduction. | et |
| dc.identifier.uri | http://hdl.handle.net/10062/72918 | |
| dc.language.iso | eng | et |
| dc.publisher | Tartu Ülikool | et |
| dc.rights | embargoedAccess | et |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
| dc.subject | Budding yeast | et |
| dc.subject | cell cycle | et |
| dc.subject | Cdk | et |
| dc.subject | Clb5 | et |
| dc.subject | SLiM | et |
| dc.subject | Sld2 | et |
| dc.subject.other | magistritööd | et |
| dc.title | Analysis of the docking interaction between Sld2 and Clb5 in budding yeast | et |
| dc.type | Thesis | et |