The N-terminus of Melanoma-associated antigen A10 interacts with peripheral nucleoporins

dc.contributor.advisorKurg, Reet, juhendaja
dc.contributor.authorNesterovich, Alexey
dc.contributor.otherTartu Ülikool. Loodus- ja täppisteaduste valdkondet
dc.contributor.otherTartu Ülikool. Tehnoloogiainstituutet
dc.date.accessioned2024-06-18T07:48:52Z
dc.date.available2024-06-18T07:48:52Z
dc.date.issued2024
dc.description.abstractShowing common features of tumorigenesis, Melanoma-associated antigen A10 (MAGEA10) possesses the potential for cancer therapy. MAGEA10 is a highly immunogenic MAGEA family member that acts as a hub protein and is associated with global hypomethylation. The N-terminus of MAGEA10 is involved in its expression, nuclear transport, and electrophoretic mobility shift. This thesis aims to characterise further the N-terminus of MAGEA10 and find its potential interaction partners.
dc.identifier.urihttps://hdl.handle.net/10062/99919
dc.language.isoen
dc.publisherTartu Ülikoolet
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Estoniaen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/ee/
dc.subjectTumorigenesis
dc.subjectMelanoma-associated antigen
dc.subjectN-terminus
dc.subjectProtein-protein interaction
dc.subject.othermagistritöödet
dc.titleThe N-terminus of Melanoma-associated antigen A10 interacts with peripheral nucleoporins
dc.title.alternativeMelanoomi-seoselise antigeeni A10 N-terminaalne ots interakteerub perifeersete tuumapoori valkudega
dc.typeThesisen

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